Seven students from the Izhevsk school, which has roughly 1,000 students, were victims.
It is unknown why the shooter killed himself, according to reports. There are emergency personnel on the site.
Videos that have been published by Russian media seem to depict chaos inside the structure where the shooting occurred.
In some of the video, kids can be seen huddling beneath desks and there is blood on the floor of the classroom and a gunshot hole in the window.
Russian authorities have said that the dead include two teachers and two security personnel. The school buildings have been cleared of both staff and students.
According to a local MP, the attacker carried two loaded firearms. Investigators claimed that the shooter was wearing a balaclava and a T-shirt with a Nazi insignia, according to state news outlet Tass.
The region's chief has declared a time of mourning that will last until September 29.
The school is near to the main government structures in Izhevsk, a city with about 650,000 population.
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